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Taxifolin

SKU: orb1307570

Description

Taxifolin (Dihydroquercetin) is a bioactive flavonoid found in plants like Siberian larch. It is widely used in research for its antioxidant properties, with applications in cardiovascular, metabolic, and inflammation studies conducted in both cellular and animal models.

Research Area

Cardiovascular Research, Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

CAS Number480-18-2
MW304.25
Purity98.90% (May vary between batches)
FormulaC15H12O7
SMILESO[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c1ccc(O)c(O)c1
TargetTyrosinase,Autophagy,TNF,Adrenergic Receptor,VEGFR
SolubilityH2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:65 mg/mL (213.64 mM);Ethanol:56 mg/mL (184.06 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.57 mM)

Bioactivity

Target IC50
Collagenase:193.3 μM
In Vivo
Taxifolin is easily metabolized, and its metabolites are prevalent in vivo, although limited data exists on its in vivo metabolism. Metabolites with the same fragment pattern may share the same pharmacophore, exerting the same pharmacological effects as taxifolin through an additive effect on the same drug targets. Thus, taxifolin is bioactive in both its parent form and through its metabolites.

Storage & Handling

Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

VEGFR2, Tyrosinase, β-adrenergic receptor, TNF-α, Taxifolin, Inhibitor, inhibit, Dihydroquercetin, Collagenase Tyrosinase, antifibrotic, antioxidant, Autophagy, Beta-nerve growth factor, (+)-Dihydroquercetin, (+)-Taxifolin, AdrenergicReceptor, Adrenergic Receptor

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Key Properties

No computed properties available.

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Taxifolin (orb1307570)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

25 mg
$ 70.00
1 ml x 10 mM (in DMSO)
$ 90.00
50 mg
$ 90.00
100 mg
$ 110.00
500 mg
$ 210.00
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