Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

SKU: orb1984528

Description

This modified tenofovir prodrug exhibits enhanced metabolic stability with a longer half-life in human liver microsomes and potent anti-HIV activity in vitro. Its improved pharmacokinetic profile supports research into long-acting antiviral therapies, making it a valuable tool for in vivo efficacy and mechanism of action studies.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Images & Validation

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Key Properties

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CAS Number	2611373-74-9
MW	626.855
Formula	C₂₉H₅₅N₆O₅PSi
SMILES	N.C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(=O)OCCCOCCCCCCCCCCCCC#C[Si](C)(C)C
Target	HIV Protease,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

166628172 ↗

Key Properties

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No computed properties available.

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