Thalidomide-4-OH-C11-OH

SKU: orb3027458

Description

Thalidomide-4-OH-C11-OH is a conjugate of an E3 ligase ligand and a linker (E3LigaseLigand-Linker Conjugates), comprising Thalidomide-4-OH and the corresponding linker. Thalidomide-4-OH-C11-OH acts as a Cereblon ligand to recruit CRBN protein and serves as a key intermediate for synthesizing complete PROTAC molecules, such as PROTAC GPX4 degrader-4.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	3071165-50-6
MW	444.52
Formula	C₂₄H₃₂N₂O₆
SMILES	O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCCCCCCCCCCO)C3C2=O)CC1
Target	E3 Ligase Ligand-Linker Conjugates

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

E3 Ligase Ligand-Linker Conjugates

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