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Thalidomide-5-CH2-NH2 hydrochloride

SKU: orb1909106

Description

Thalidomide-5-CH2-NH2 (hydrochloride) is a cereblon (CRBN)-binding ligand used to construct PROTAC degraders. This small molecule enables targeted protein degradation and is a key tool for probing protein function in both cellular and in vivo disease models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1010100-22-7
MW323.73
FormulaC14H14ClN3O4
SMILESCl.O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2=O)CN)CC1
TargetAutophagy,Others,E3 Ligase Ligand-Linker Conjugates,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Thalidomide-5-CH2-NH2 hydrochloride (orb1909106)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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