Timcodar mesylate

SKU: orb2564361

Description

Timcodar mesylate (VX-853-2) and its analog VX-710 function as inhibitors of mammalian multidrug-resistant bacterial efflux pumps, specifically blocking the efflux of ethidium bromide in Staphylococcus aureus. This capability suggests that Timcodar mesylate may boost the efficacy of antibiotics by impeding the bacterial efflux pumps, therefore lowering the minimum inhibitory concentrations of certain antibiotics against Gram-positive pathogens including Staphylococcus aureus, Enterococcus, and Streptococcus pneumoniae.

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Key Properties

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CAS Number	183313-30-6
MW	941.50
Formula	C₄₅H₅₃ClN₄O₁₂S₂
SMILES	CS(=O)(O)=O.ClC(C=C1)=CC=C1C[C@H](N(C)C(C(C2=CC(OC)=C(C(OC)=C2)OC)=O)=O)C(N(CC3=CC=CC=C3)C(CCC4=CC=NC=C4)CCC5=CC=NC=C5)=O.CS(=O)(O)=O
Target	Others

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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