TJP3 (N) Antibody, Rabbit Polyclonal

SKU: orb131878

Description

Rabbit polyclonal to TJP3. Tight junction protein 3 (TJP3) is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. TJP3 plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms of TJP3.

Research Area

Epigenetics

Images & Validation

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Tested Applications	IP, WB
Dilution Range	WB:1:1000-1:3000
Reactivity	Human
Application Notes	WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human TJP3.

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	N-terminal region of human TJP3
Molecular Weight	103
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Concentration	100 μg/ml BSA
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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anti Tight junction protein ZO-3 antibody, anti Tight junction protein 3 antibody, anti Zona occludens protein 3 antibody, anti Zonula occludens protein 3 antibody, anti ZO3 antibody

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Quick Database Links

UniProt

O95049

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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Immunoprecipitation

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