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Tomivosertib HCl

SKU: orb1739356

Description

Tomivosertib (eFT508) is a selective MNK1/2 inhibitor that blocks the phosphorylation of eIF4E, thereby modulating the translation of mRNAs involved in oncogenesis and immune response. It has demonstrated activity in preclinical in vitro and in vivo models of cancer and inflammation.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

CAS Number1849590-02-8
MW376.845
FormulaC17H21ClN6O2
SMILESCl.Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1
TargetMNK,Others,PD-1/PD-L1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Tomivosertib HCl (orb1739356)

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