Topoisomerase II inhibitor 3

SKU: orb1688755

Description

Compound 6 h is an acridone-based topoisomerase IIα/β inhibitor (IC50 = 0.17 and 0.23 μM, respectively). It induces DNA damage, apoptosis, and loss of mitochondrial membrane potential, making it a useful tool for cancer research in both cellular and biochemical studies.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	99140-25-7
MW	356.38
Formula	C₁₈H₂₀N₄O₄
SMILES	N(=O)(=O)C1=C2C(=C(NCCCN(C)C)C=C1)C(=O)C=3C(N2)=CC=C(O)C3
Target	Others,Apoptosis,Topoisomerase

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

13753489 ↗

Key Properties

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No computed properties available.

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