trans-Urocanic Acid

SKU: orb1692800

Description

trans-Urocanic acid, the (E)-isomer of the epidermal UV-protectant, is enriched in brain regions like the hippocampus. This immunomodulatory compound inhibits human natural killer cell activity in vitro and serves as a research tool in neuroscience, particularly for Alzheimer's disease studies.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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CAS Number	3465-72-3
MW	138.12
Purity	99.82% (May vary between batches)
Formula	C₆H₆N₂O₂
SMILES	C(=C/C(O)=O)\C1=CN=CN1
Target	Others,Endogenous Metabolite
Solubility	DMF:3 mg/mL (21.72 mM);PBS (pH 7.2):0.3 mg/mL (2.17 mM);DMSO:15 mg/mL (108.6 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (14.48 mM)

Bioactivity

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In Vitro	In primary human keratinocytes, trans-Urocanic acid (100 μg/mL; 24 hours) reduces cell proliferation and viability.

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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trans Urocanic Acid, trans-UCA, transUrocanic Acid, trans-Urocanic Acid, (E)-Urocanic acid

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Compound Identifiers

PubChem CID

736715 ↗

Key Properties

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No computed properties available.

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