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Urumin

SKU: orb2277202

Description

Urumin is a small-molecule antiviral agent that potently inhibits influenza A virus (H1 strains, including PR8) with an IC50 of 3.8 µM by targeting the conserved hemagglutinin stalk. It neutralizes drug-resistant viruses and has demonstrated in vivo protective efficacy against lethal influenza infection in murine models.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

TargetInfluenza Virus
CAS Number2215863-74-2
MW2961.34
FormulaC129H198N42O35S2
SMILESC([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CS)=O)C)=O)[C@H](CC)C)=O)C)=O)=O)CC(N)=O)=O)CO)=O)=O)CCCNC(=N)N)=O)=O)CS)=O)CCC(N)=O)=O)CO)=O)CC(O)=O)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@H]([C@H](CC)C)N)=O)CCC4)CC(C)C)=O)CCCNC(=N)N)=O)=O)C)=O)=O)[C@H](CC)C)=O)CC(N)=O)=O)=O)CCCNC(=N)N)=O)C=5C=6C(NC5)=CC=CC6

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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Urumin (orb2277202)

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