Val-Ala-PABC-Exatecan trifluoroacetate

SKU: orb2283474

Description

Val-Ala-PABC-Exatecan trifluoroacetate is a drug-linker conjugate for antibody-drug conjugates (ADC), comprising a cleavable Tesirine linker, Val-Ala-PABC, and the topoisomerase I inhibitor Exatecan. This compound facilitates the synthesis of ADC molecules, including Mal-PEGn-amide-va-Exatecan.

Research Area

Molecular Biology

Images & Validation

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Key Properties

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CAS Number	2928571-45-1
MW	868.83
Formula	C₄₂H₄₄F₄N₆O₁₀
SMILES	C(C(O)=O)(F)(F)F.N(C(OCC1=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)C)=O)C=C1)=O)[C@@H]2C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=C(CC2)C(C)=C(F)C7
Target	Drug-Linker Conjugates for ADC,Topoisomerase

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

Drug-Linker Conjugates for ADC,Topoisomerase

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