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Vem-L-Cy5

SKU: orb2278413

Description

Vem-L-Cy5 (compound 3), a Vemurafenib-based BRAF inhibitor conjugated with the near-infrared (NIR) fluorophore cyanine-5 (Cy5), selectively targets the BRAF V600E mutation and inhibits MEK phosphorylation. This compound demonstrates cell permeability and has been shown to inhibit the growth of various cancer cell types.

Research Area

Signal Transduction

Images & Validation

Key Properties

MW1194.31
FormulaC63H68F5N7O9S
SMILESCC(C1=C(N/2CCCCCC(NCCOCCOCC(NC3=CC=C(C4=CN=C(NC=C5C(C6=C(F)C=CC(NS(=O)(CCC)=O)=C6F)=O)C5=C4)C=C3)=O)=O)C=CC=C1)(C)C2=C/C=C/C=C/C7=[N+](C)C(C=CC=C8)=C8C7(C)C.FC(F)(F)C([O-])=O
TargetRaf

Storage & Handling

Storage-20°C
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

Vem-L-Cy5 (orb2278413)

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