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Vemurafenib-d7

SKU: orb3138623

Description

Vemurafenib-d7 is the deuterated form of Vemurafenib. Vemurafenib (PLX4032; RG7204; RO5185426) is a pioneering and potent selective inhibitor of B-RAF, effectively suppressing the activity of RAFV600E and c-RAF-1 with IC50 values of 31 nM and 48 nM, respectively. It is capable of inducing cellular autophagy (autophagy).

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Key Properties

CAS Number1365986-73-7
MW496.97
FormulaC23H18ClF2N3O3S
SMILESC(=O)(C=1C=2C(NC1)=NC=C(C2)C3=CC=C(Cl)C=C3)C4=C(F)C(NS(C(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H])(=O)=O)=CC=C4F
TargetRaf,Autophagy

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Vemurafenib-d7 (orb3138623)

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