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Zeleciment basivarsen

SKU: orb3136946

Description

Zeleciment basivarsen (DYNE-101) is an antibody oligonucleotide conjugate (AOC), consisting of a Fab antibody named Zeleciment that binds to the transferrin receptor 1 (TfR1) on muscle cells, and an antisense oligonucleotide known as Basivarsen. This compound targets the RNA of the mutant dystrophia myotonica-protein kinase (DMPK) for RNase H-mediated degradation, and is utilized in the study of myotonic dystrophy type 1 (DM1).

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Key Properties

CAS Number2767191-74-0
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Zeleciment basivarsen (orb3136946)

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