TNF-α agonistic 1

SKU: orb1819255

Description

This small molecule TNF-α agonist, 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea, stimulates cellular TNF-α secretion. It is a research tool for studying TNF-α signaling pathways and inflammation in both in vitro and in vivo experimental models.

Research Area

Cell Biology

Images & Validation

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Key Properties

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CAS Number	2379727-88-3
MW	487.9
Purity	98.61% (May vary between batches)
Formula	C₂₄H₂₁ClF₃N₅O
SMILES	N(C(NC1=CC(C(F)(F)F)=C(Cl)C=C1)=O)C2CC=3C=4C(NC3CC2)=CC(=CC4)C5=CN(C)N=C5
Target	TNF,Others
Solubility	DMSO:55 mg/mL (112.73 mM)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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1(4chloro3(trifluoromethyl)phenyl)3(7(1methyl1Hpyrazol4yl)2,3,4,9tetrahydro1Hcarbazol3yl)urea, TNF-α

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Compound Identifiers

PubChem CID

155556142 ↗

Key Properties

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No computed properties available.

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