1-Linoleoyl Glycerol

SKU: orb1310082

Description

1-Linoleoyl Glycerol (Monolinolein), isolated from Saururus chinensis roots, is a chiral glycerol monoester. Its (R)- and (S)-enantiomers act as inhibitors of Lipoprotein-associated phospholipase A2 (Lp-PLA2), exhibiting IC50 values of 45.0 µM and 52.0 µM, respectively. This compound is utilized in biochemical research to study Lp-PLA2's role in inflammation and vascular diseases.

Research Area

Immunology & Inflammation, Metabolism Research

Images & Validation

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Key Properties

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CAS Number	2277-28-3
MW	354.52
Purity	99.56% (May vary between batches)
Formula	C₂₁H₃₈O₄
SMILES	CCCCCC=CCC=CCCCCCCCC(=O)OCC(O)CO
Target	Phospholipase,Interleukin
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.31 mM);Ethanol:88 mg/mL (248.22 mM);DMSO:88 mg/mL (248.22 mM)

Bioactivity

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Target IC50	Lp-PLA2:45.0 μM((R)-1-Linoleoyl Glycerol)\|Lp-PLA2:52.0 μM((S)-1-Linoleoyl Glycerol)

Storage & Handling

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Storage	store at low temperature \| Pure form: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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1-Monolinolein, 1Linoleoyl Glycerol, 1-Linoleoyl Glycerol, 1-Linoleoyl-rac-glycerol, 1 Linoleoyl Glycerol, Lp-PLA2, inhibit, Inhibitor, Monolinolein, Glycerol 1-monolinolate, Glyceryl monolinoleate, Phospholipase

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Compound Identifiers

PubChem CID

117319 ↗

Key Properties

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No computed properties available.

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