10-Methoxy-canthin-6-one

SKU: orb2665032

Description

10-Methoxy-canthin-6-one is a DNA-intercalating agent that induces DNA damage, leading to G2/M cell cycle arrest and subsequent differentiation in acute myeloid leukemia (AML) and leukemia stem cells (LSCs). This small molecule is a valuable research tool for studying myeloid differentiation and p38 MAPK signaling in both in vitro and in vivo leukemia models.

Research Area

Signal Transduction

Images & Validation

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Key Properties

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CAS Number	86293-40-5
MW	250.25
Formula	C₁₅H₁₀N₂O₂
SMILES	O=C1C=CC2=NC=CC=3C4=CC(OC)=CC=C4N1C23
Target	p38 MAPK

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

158928 ↗

Key Properties

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No computed properties available.

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