1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin

SKU: orb2276877

Description

1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin, a polychlorinated dibenzodioxin (PCDD), acts as an agonist for the aryl hydrocarbon receptor (AhR; EC50s = 5.4 and 9.3 nM at 4 and 8 h, respectively, in a reporter assay). It has been observed to reduce antibody production against sheep red blood cells in mice at doses of 0.5 and 2 µg/kg. This compound has been detected in animal feed and in the vicinity of municipal waste incinerators.

Images & Validation

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Key Properties

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CAS Number	57653-85-7
MW	390.86
Formula	C₁₂H₂Cl₆O₂
SMILES	ClC1=C(Cl)C=C2OC3=C(C=C(C(Cl)=C3Cl)Cl)OC2=C1Cl

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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