1,3,5-Trihydroxy-4-prenylxanthone

SKU: orb1689954

Description

This prenylated xanthone is a phosphodiesterase 5 (PDE5) inhibitor (IC50 = 3.0 µM) and also exhibits cholinesterase inhibitory activity. It functions as an anti-inflammatory agent by suppressing LPS-induced NF-κB and AP-1 signaling pathways through interference with IRAK-1 posttranslational modification. This makes it a useful research tool for studying PDE-related, neurochemical, and innate immune signaling processes.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	53377-61-0
MW	312.32
Formula	C₁₈H₁₆O₅
SMILES	C(C=C(C)C)C1=C2C(C(=O)C=3C(O2)=C(O)C=CC3)=C(O)C=C1O
Target	Sodium Channel,PDE,NO Synthase

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

10335672 ↗

Key Properties

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No computed properties available.

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