Cart summary

You have no items in your shopping cart.

1V209

SKU: orb1299043

Description

1V209

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number1062444-54-5
MW359.34
Purity99.61%
FormulaC16H17N5O5
SMILESCOCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(cc3)C(O)=O)c2n1
TargetTLR
SolubilityDMSO:83.33 mg/mL (231.9 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.18 mM)

Bioactivity

In Vivo
I the in vivo immunization study, 1V209-αMan-GNPs induced significantly higher titers of IgG2c antibody specific to ovalbumin as an antigen than did unconjugated 1V209, and splenomegaly and weight loss were not observe.
In Vitro
The s All molecule synthetic TLR7 li and 2-methoxyethoxy-8-oxo-9-(4-carboxy benzyl)adenine (1V209), and α-mannose were coimmobilized via linker molecules consisting of thioctic acid o the GNP surface (1V209-αMan-GNPs) the in vitro cytokine production activity of 1V209-αMan-GNPs was higher than that o the unconjugated 1V209 derivative in mouse bone marrow-derived dendritic cells and in human peripheral blood mononuclear cell.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

conjugate, cell, 1V 209, 1V209, 1V-209, cancer, inhibit, IP-10, intravenous, IL-6, Inhibitor, MCP-1, polysaccharides, TLR7 agonist T7, TLR7, TLR, Toll-like Receptor (TLR), TNFα, Tumor
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

1V209 (orb1299043)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 90.00
5 mg
$ 90.00
10 mg
$ 120.00
25 mg
$ 220.00
50 mg
$ 290.00
100 mg
$ 400.00
200 mg
$ 550.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry