2-[6-[[(3S)-1-Ethyl-3-piperidinyl]amino]-3-pyridazinyl]-3-methyl-5-(trifluoromethyl)phenol

SKU: orb3172853

Description

2-[6-[[(3S)-1-Ethyl-3-piperidinyl]amino]-3-pyridazinyl]-3-methyl-5-(trifluoromethyl)phenol is a small-molecule NLRP3 inflammasome inhibitors centered on the pyrazine-3-ylphenol structure. By interfering with the activation or assembly of the 2-[6-[[(3S)-1-Ethyl-3-piperidinyl]amino]-3-pyridazinyl]-3-methyl-5-(trifluoromethyl)phenol reduce the activation of caspase-1 and the release of pro-inflammatory factors such as IL-1β.

Images & Validation

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Key Properties

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CAS Number	2557366-30-8
MW	380.41
Formula	C₁₉H₂₃F₃N₄O
SMILES	CC1=C(C(O)=CC(C(F)(F)F)=C1)C2=CC=C(N[C@@H]3CN(CC)CCC3)N=N2
Target	IL Receptor,Caspase,NOD

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

IL Receptor,Caspase,NOD

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