2-O-Acetyl-20-hydroxyecdysone

SKU: orb1684886

Description

2-O-Acetyl-20-hydroxyecdysone is a natural ecdysteroid found in plants and insects. It exhibits neuroprotective properties by mitigating amyloid-β42-induced cytotoxicity, redirecting Aβ aggregation toward less toxic fibrils instead of oligomers. This makes it a valuable research tool for in vitro studies of Alzheimer's disease pathology and neuroprotective mechanisms.

Research Area

Neuroscience

Images & Validation

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Key Properties

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CAS Number	19536-25-5
MW	522.67
Purity	99.99% (May vary between batches)
Formula	C₂₉H₄₆O₈
SMILES	[H][C@@]1(CC[C@@]2(O)C3=CC(=O)[C@]4([H])C[C@@H](O)[C@H](C[C@]4(C)[C@@]3([H])CC[C@]12C)OC(C)=O)[C@@](C)(O)[C@H](O)CCC(C)(C)O
Target	Beta Amyloid
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.31 mM);DMSO:90 mg/mL (172.19 mM)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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bAmyloid, Aβ, b Amyloid, 2-O-Acetyl-20-hydroxyecdysone, 20-Hydroxyeedysone, 20-Hydroxyeedysone 2-acetate, BetaAmyloid, Beta Amyloid, βAmyloid, β Amyloid

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Compound Identifiers

PubChem CID

11060408 ↗

Key Properties

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No computed properties available.

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