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2,4,6-Trihydroxybenzaldehyde

SKU: orb1940120

Description

2,4,6-Trihydroxybenzaldehyde is a natural product. 2,4,6-Trihydroxybenzaldehyde, a potential anti-obesity treatment, suppressed adipocyte differentiation in 3T3-L1 cells and fat accumulation induced by high-fat diet in C57BL/6 mice. It is also a potent antidiabetic agent. 2,4,6-Trihydroxybenzaldehyde has potential anticancer activity.

Images & Validation

Key Properties

CAS Number487-70-7
MW154.121
Purity>98% (HPLC)
FormulaC7H6O4
SMILESOc1cc(O)c(C=O)c(O)c1

Bioactivity

In Vivo
2, 4, 6-Trihydroxybenzaldehyde (oral administration; 5 and 25 mg/kg for 13 weeks) reduces the HFD-induced increase in weight gain, reduces serum levels of glucose, triglycerides, and total cholesterol.
In Vitro
2, 4, 6-Trihydroxybenzaldehyde inhibits adipocyte differentiation and lipid accumulation in 3T3-L1 cells.2, 4, 6-Trihydroxybenzaldehyde down-regulates PPARγ, C/EBPα, SREBP-1c, and FAS protein expression levels.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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2,4,6-Trihydroxybenzaldehyde (orb1940120)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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