(3R,5R)-3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane 3-O-β-D-glucopyranoside

SKU: orb3179571

Description

(3R,5R)-3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane 3-O-β-D-glucopyranoside is a diarylheptane glycoside extracted from Tacca plantaginea. This compound significantly inhibits TNF-α-induced NF-κB transcriptional activity with an IC50 of 9.4 μM and notably activates PPAR transcriptional activity with an EC50 of 9.9 μM, showing specific activation of PPARβ(δ) with an EC50 of 23.1 μM. At the tested concentrations, it is non-toxic to cells and can be applied in research related to inflammatory diseases.

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Key Properties

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CAS Number	408324-05-0
MW	510.54
Formula	C₂₅H₃₄O₁₁
SMILES	O([C@H](CCC1=CC(O)=C(O)C=C1)C[C@@H](CCC2=CC(O)=C(O)C=C2)O)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O
Target	NF-κB,PPAR

Storage & Handling

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Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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NF-κB,PPAR

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