4-Hydroxyresveratrol

SKU: orb2944423

Description

4-Hydroxyresveratrol (3,4,5,4'-Tetrahydroxystibene) is a resveratrol analog that variably induces the expression of pro-apoptotic genes such as p53 and Bax. It triggers apoptosis in SV40 virus-transformed WI38 cells (WI38VA), but not in WI38 cells. Additionally, 4-Hydroxyresveratrol significantly increases the expression of p53, GADD45, and Bax genes in WI38VA cells, while suppressing the expression of the bcl-2 gene.

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Key Properties

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CAS Number	331443-00-6
MW	244.243
Formula	C₁₄H₁₂O₄
SMILES	C(=C/C1=CC=C(O)C=C1)\C2=CC(O)=C(O)C(O)=C2
Target	Apoptosis,MDM-2/p53,Bcl-2 Family

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

Apoptosis,MDM-2/p53,Bcl-2 Family

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