4beta-Hydroxywithanolide E

SKU: orb1683481

Description

4β-Hydroxywithanolide E (4bHWE) is a natural compound with demonstrated anti-tumor and anti-inflammatory properties. It inhibits colon cancer cell and spheroid growth by modulating splicing factors and histone modifications, while in vivo studies show it attenuates diabetes progression by suppressing NF-κB signaling in adipose tissue.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Signal Transduction

Images & Validation

−

Key Properties

−

CAS Number	54334-04-2
MW	502.604
Formula	C₂₈H₃₈O₈
SMILES	[H][C@@]12C[C@]3([H])[C@]([H])(CC[C@@]4(C)[C@@]3(O)CC[C@@]4(O)[C@@](C)(O)[C@@]3([H])CC(C)=C(C)C(=O)O3)[C@@]3(C)C(=O)C=C[C@H](O)[C@@]13O2 \|c:37,t:26\|
Target	NF-κB,PPAR,COX,PARP,HSP

Storage & Handling

−

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Compound Identifiers

PubChem CID

73621 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols