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6-OAU

SKU: orb1306678

Description

6-OAU (GTPL5846) is a potent and selective synthetic agonist for the GPR84 receptor. It demonstrates an EC50 of 105 nM in Gqi5-coupled in vitro phosphatidylinositol (PI) assays using HEK293 cells. This tool compound is valuable for investigating GPR84's role in immune and metabolic functions in both cellular and animal models.

Research Area

Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number83797-69-7
MW239.31
Purity99.68%
FormulaC12H21N3O2
SMILESCCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1
TargetAntibiotic,Antibacterial,ERK,GPCR
SolubilityDMSO:55 mg/mL (229.83 mM)

Bioactivity

Target IC50
GPR84:105 nM (EC50)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

chemotaxis, Cytokines, 6 OAU, 6OAU, 6-OAU, B. abortus, macrophage, Inhibitor, inhibit, inflammation, IL-8, ERK, Extracellular signal regulated kinases, GTPL 5846, GTPL5846, GTPL-5846, GTPγS, GPR84, G protein-coupled receptor, G protein coupled receptor 84, Lauric acid, MAPKs, HEK293, rat air pouch model, Sf9, PMN, proinflammatory cytokine, TNF-α, U937

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    83797-69-7

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    C12H21N3O2

    1 g, 500 mg, 200 mg, 50 mg, 100 mg, 10 mg, 25 mg, 2 mg, 5 mg
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Key Properties

No computed properties available.

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Protocol Information

6-OAU (orb1306678)

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% DMSO +
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% Tween 80 +
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Available Sizes

Select a size below

1 mg
$ 210.00
2 mg
$ 270.00
1 ml x 10 mM (in DMSO)
$ 360.00
5 mg
$ 390.00
10 mg
$ 540.00
25 mg
$ 840.00
50 mg
$ 1,170.00
100 mg
$ 1,560.00
DispatchUsually dispatched within 3-5 working days
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