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6PPD-Q

SKU: orb2278596

Description

6PPD-Q (6PPD-Quinone) is an environmental pollutant that can target CNR2, CNR1, AA2AR, LCAT and TRPA1. Among them, CNR2 has the highest binding affinity and may act as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q can damage the sperm quality and induce the impairment of male reproductive ability in mice. 6PPD-Q can induce intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolytic metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2754428-18-5
MW298.38
Purity98.43%
FormulaC18H22N2O2
SMILESO=C1C=C(NC(C)CC(C)C)C(=O)C=C1NC=2C=CC=CC2
TargetEndogenous Metabolite

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

6PPD-Q (orb2278596)

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