7-Methoxyrosmanol

SKU: orb1297478

Description

7-Methoxyrosmanol

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	113085-62-4
MW	360.44
Purity	98.40%
Formula	C₂₁H₂₈O₅
SMILES	[H][C@@]12[C@@H]3OC(=O)[C@@]1(CCCC2(C)C)c1c(O)c(O)c(cc1[C@@H]3OC)C(C)C
Target	Others,cAMP
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.55 mM);DMSO:12 mg/mL (33.29 mM)

Bioactivity

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In Vitro

In order to find new effective HIV protease inhibitors, two diterpenes (carnosic acid and carnosol) were isolated from rosemary (Rosmarinus officinalis L.), and rosmanol and semisynthetic derivatives (7-Methoxyrosmanol 7-O-ethylrosmanol, and 11,12-O,O-dimethylcarnosol) were prepared. The inhibitory activity of all six compounds against HIV-1 protease was tested. The carnosic acid showed the strongest inhibitory effect (IC90 = 0.08 micrograms/ml). The same compound was also assayed against HIV-1 virus replication (IC90 = 0.32 micrograms/ml).

Storage & Handling

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Storage	keep away from direct sunlight,keep away from moisture,The compound is unstable in solution. Please use soon \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Inhibitor, inhibit, cAMP, 7 Methoxyrosmanol, 7-O-Methylrosmanol, 7Methoxyrosmanol, 7-Methoxyrosmanol

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Compound Identifiers

PubChem CID

23243692 ↗

Key Properties

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No computed properties available.

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