7β,27-dihydroxy Cholesterol

SKU: orb1693257

Description

7β,27-dihydroxycholesterol is a selective endogenous agonist for RORγ and RORγt, activating receptor signaling and enhancing IL-17A production in both human Th17 cells and mouse γδ T cells in vitro and in vivo. This oxysterol is a valuable research tool for studying Th17 biology, autoimmunity, and RORγt-related transcriptional regulation.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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CAS Number	240129-43-5
MW	418.65
Formula	C₂₇H₄₆O₃
SMILES	C[C@@H](CO)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Target	ROR,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

52931518 ↗

Key Properties

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No computed properties available.

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