A2AR-antagonist-1

SKU: orb1744781

Description

A2AR-antagonist-1 is an orally bioavailable, potent A2A receptor antagonist (IC50 = 29 nM) with demonstrated metabolic stability. It exhibits anti-tumor activity by reversing T-cell suppression, downregulating LAG-3/TIM-3 and upregulating effector molecules like IFN-γ and Granzyme B, making it a valuable tool for immuno-oncology research.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	2922920-71-4
MW	451.52
Formula	C₂₇H₂₅N₅O₂
SMILES	CC1=C(C=CC=C1C2=NC(=NC(=C2)C3=CC(=O)N(C=C3)CC4=CC(=CC=C4)C(C)(C)O)N)C#N
Target	Adenosine Receptor

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

168007153 ↗

Key Properties

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No computed properties available.

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