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Abz-FR-K(Dnp)-P-OH

SKU: orb1983859

Description

This small molecule is a highly efficient substrate for angiotensin I-converting enzyme (ACE), exhibiting a Km of 4.0 µM and a kcat of 210 s⁻¹. It is widely used in vitro for kinetic assays and inhibitor screening to study cardiovascular and renal systems, facilitating research into hypertension and heart failure pathways.

Research Area

Metabolism Research

Images & Validation

Key Properties

TargetAngiotensin-converting Enzyme (ACE)
CAS Number500799-61-1
MW831.87
FormulaC39H49N11O10
SMILESNC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1N)C(=O)N[C@@H](CCCCNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O)C(=O)N1CCC[C@H]1C(O)=O

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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Abz-FR-K(Dnp)-P-OH (orb1983859)

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