ACHP

ACHP (IKK-2 Inhibitor VIII) is a selective IKK-α/β inhibitor that blocks NF-κB activation. It exhibits anti-HIV-1 activity by suppressing TNF-α-induced recruitment of NF-κB (p65) to the HIV-1 LTR, thereby inhibiting viral gene expression. This compound is a valuable tool for studying NF-κB signaling in inflammation and viral pathogenesis research.