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ACP-5862

SKU: orb1710493

Description

ACP-5862 is the major active metabolite of Acalabrutinib, featuring a pyrrolidine ring-opened structure and exhibiting potent BTK inhibition (IC50: 5.0 nM). This metabolite is valuable for research into the pharmacokinetics, efficacy, and mechanism of action of BTK inhibitors in both cellular and animal models of B-cell malignancies.

Research Area

Cardiovascular Research, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number2230757-47-6
MW481.51
FormulaC26H23N7O3
SMILESCC#CC(=O)NCCCC(=O)c1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)nccn12
TargetCytochromes P450,BTK,Drug Metabolite

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

ACP-5862 (orb1710493)

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