Albanol B

SKU: orb3054667

Description

Albanol B is an arylbenzofuran derivative which can be isolated from mulberries. Albanol B exhibits anti-Alzheimer's disease, anti-bacterial and antioxidant activities.

Images & Validation

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Key Properties

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CAS Number	87084-99-9
MW	558.53
Purity	>98% (HPLC)
Formula	C₃₄H₂₂O₈

Bioactivity

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In Vivo

Animal model: EX-3LL tumor-bearing mice. Dosage: 50 mg/kg, 100 mg/kg. Administration: IP; once daily for 21 days. Result: Decreased tumor volume and weight by 48.0% and 41.0% (for 50 mg/kg treatment), and 61.3% and 57.3% (for 100 mg/kg treatment), respectively.

In Vitro

Cell Viability Assay Cell line: A549 cells, BZR, NCI-H1975, and NCI-H226 cells. Concentration: 0, 1, 3, 10, and 30 μM. Incubation time: 48 hours. Result: Exhibited inhibitory effects on cancer cells with IC50s of 5.6 μM (A549), 8.9 μM (BZR), 12.7 μM (NCI-H1975), and 15 μM (NCI-H226), respectively. Cell Cycle Analysis Cell line: A549 and H1975 cells. Concentration: 1, 3, 10 μM. Incubation time: 48 hours. Result: Increased cells in G2/M phase from 9.5% to 14.34%, 18.13% and 47.9%, respectively. Western blot analysis. Cell line: A549 cells. Concentration: 1 h, 3 h, 6 h, and 9 h. Incubation time: 48 hours. Result: Increased the phosphorylation levels of ERK1/2 and AKT in time- and concentration-dependent manners.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Albanol B (orb3054667)

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Albanol B

Description

Images & Validation

Key Properties

Bioactivity

Storage & Handling

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