Alkynyl Palmitic Acid

SKU: orb1217412

Description

Alkynyl Palmitic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Images & Validation

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Key Properties

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CAS Number	99208-90-9
MW	252.39
Purity	>98% (HPLC)
Formula	C₁₆H₂₈O₂
SMILES	C#CCCCCCCCCCCCCCC(O)=O
Target	PROTAC
Solubility	DMSO:100 mg/mL (396.21 mM; Need ultrasonic)

Bioactivity

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In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

PROTAC

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