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AMG-47a

SKU: orb1220556

Description

AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.

Images & Validation

Key Properties

CAS Number882663-88-9
MW535.56
Purity>98% (HPLC)
FormulaC29H28F3N5O2
SMILESCc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1ccc2nc(NCCN3CCOCC3)ncc2c1
TargetSrc
SolubilityDMSO:34 mg/mL (63.48 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • AMG-47a [orb1300050]

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    882663-88-9

    535.56

    C29H28F3N5O2

    1 mg, 1 ml x 10 mM (in DMSO), 50 mg, 100 mg, 5 mg, 10 mg, 25 mg
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AMG-47a (orb1220556)

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Available Sizes

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200 mg
500 mg
5 mg
$ 150.00
10 mg
$ 230.00
25 mg
$ 370.00
50 mg
$ 530.00
100 mg
$ 760.00