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Aminophylline

SKU: orb1307767

Description

Aminophylline is a bronchodilator that acts as a competitive, non-selective phosphodiesterase (PDE) inhibitor. It is widely used in respiratory research, both in vitro and in vivo, to study airway relaxation and the mechanisms of asthma and COPD.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number317-34-0
MW420.43
Purity99.94%
Formula2C7H8O2·C2H8N2
SMILESNCCN.Cn1c2c([nH]cn2)c(=O)n(C)c1=O.Cn1c2c([nH]cn2)c(=O)n(C)c1=O
TargetAdenosine Receptor,PDE
SolubilityH2O:13.7 mg/mL (32.59 mM);DMSO:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

Target IC50
PDE:0.12 mM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Phosphodiesterase (PDE), phosphodiesterase, Phyllocontin, AdenosineReceptor, Adenosine Receptor, Aminophylline, Inhibitor, inhibit, PDE, P1 receptor

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Key Properties

No computed properties available.

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Aminophylline (orb1307767)

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% Tween 80 +
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1 g
$ 70.00
DispatchUsually dispatched within 3-5 working days
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