Andrographolide

SKU: orb1304874

Description

Andrographolide, a bioactive diterpenoid from Andrographis paniculata, acts as an irreversible NF-κB antagonist. It exhibits anti-inflammatory, anti-platelet, and potential antineoplastic activities, making it a valuable tool for research in oncology, immunology, and cardiovascular disease using both in vitro and in vivo models.

Research Area

Cell Biology, Infectious Disease & Virology, Signal Transduction

Images & Validation

−

Key Properties

−

CAS Number	5508-58-7
MW	350.45
Purity	>99.99% (May vary between batches)
Formula	C₂₀H₃₀O₅
SMILES	C[C@]12[C@@]([C@@](CO)(C)[C@H](O)CC1)(CCC(=C)[C@H]2C/C=C/3\[C@H](O)COC3=O)[H]
Target	Influenza Virus,Parasite,NF-κB,Autophagy,SARS-CoV
Solubility	H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.41 mM);DMSO:145 mg/mL (413.75 mM);Ethanol:3.51 mg/mL (10.02 mM)

Storage & Handling

−

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

−

SARS-CoV, SARS coronavirus, SARSCoV, Andrographis, Andrographolide, Autophagy, NF-kB, NFkB, NFκB, NF-κB, Nuclear factor-κB, Nuclear factor-kappaB, inhibit, Inhibitor, Influenza Virus, InfluenzaVirus

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Compound Identifiers

PubChem CID

5318517 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols