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Antcin B

SKU: orb3024656

Description

Antcin B is an inhibitor of SARS-CoV-2 3-chymotrypsin-like protease (3CL Pro). It interacts with several crucial amino acid residues of 3CL Pro, including Leu141, Asn142, Glu166, and His163, through hydrogen bonding, salt bridges, and hydrophobic interactions, thereby inhibiting its activity. This inhibition blocks the cleavage of viral polyproteins and suppresses the replication of the SARS-CoV-2 virus within host cells. Antcin B shows potential for research in the context of COVID-19.

Images & Validation

Key Properties

CAS Number163597-25-9
MW468.625
FormulaC29H40O5
SMILESC[C@@]12C3=C([C@]4([C@](C)(CC3=O)[C@@]([C@@H](CCC(C(C(O)=O)C)=C)C)(CC4)[H])[H])C(=O)C[C@]1([C@H](C)C(=O)CC2)[H]
TargetSARS-CoV,Virus Protease

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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Protocol Information

Antcin B (orb3024656)

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