ERBB2/HER2/CD340 Antibody

SKU: orb1806342

Description

Anti-ERBB2 / HER2 / CD340 Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 143.9 kDa.

Images & Validation

−

Item 1 of 5

Tested Applications	ELISA, FA, FACS, In vivo
Reactivity	Human, Monkey, Mouse

Key Properties

−

Clonality	Monoclonal
Target	ERBB2 / HER2 / CD340
Source/Expression System	CHO
Molecular Weight	145.44 kDa
Purity	>95%
Purification	Protein A
Endotoxin	<0.001 EU/ug
Conjugation	Unconjugated

Storage & Handling

−

Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	100 mM Proline/Acetic acid 20mM Arginine pH 5.0
Concentration	Batch dependent
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Anti-ERBB2 / HER2 / CD340 Reference Antibody (pertuzumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

The purity of Anti-ERBB2 / HER2 / CD340 Reference Antibody (pertuzumab)is more than 99.02% ;determined by SEC-HPLC.

Immobilized human HER2(23 652) His at 2 μg/mL can bind Anti-ERBB2 / HER2 / CD340 Reference Antibody (pertuzumab);EC50=0.01375μg/mL.

BT474 cells were stained with Anti-ERBB2 / HER2 / CD340 Reference Antibody (pertuzumab) and negative control protein respectively; washed and then followed by PE and analyzed with FACS; EC98=0.2994 μg/mL.

Pertuzumab+trastuzumab inhibited the tumor growth of NCI-N87 on Balb/c nude mice. The result showed significant anti-tumor effects; with an tumor inhibition rate (TGI) of 73.8% at 5 mpk at D37.

Quick Database Links

Gene Symbol

ERBB2 / HER2 / CD340

UniProt

P04626

UniProt Details

−

No UniProt data available

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

FACS

Fluorescence-Activated Cell Sorting (FC, Flow cytometry)

View Protocol

ELISA

Enzyme-linked Immunosorbent Assay (EIA)

View Protocol

Find More Protocols