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IL-31Ra Antibody
SKU: orb1806167
Description
Images & Validation
−Item 1 of 6
| Tested Applications | ELISA, FA, FACS, In vivo |
|---|---|
| Reactivity | Human, Monkey |
Key Properties
−| Clonality | Monoclonal |
|---|---|
| Target | IL-31Ra |
| Source/Expression System | CHO |
| Molecular Weight | 144.92 kDa |
| Purity | >95% |
| Purification | Protein A |
| Endotoxin | <0.001 EU/ug |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Buffer/Preservatives | 100 mM Proline/Acetic acid 20mM Arginine pH 5.0 |
| Concentration | Batch dependent |
| Disclaimer | For research use only |
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Anti-IL-31Ra Reference Antibody (nemolizumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-IL-31Ra Reference Antibody (nemolizumab)is more than 100% ;determined by SEC-HPLC.
Immobilized human IL31R His at 2 μg/mL can bind Anti-IL-31Ra Reference Antibody (nemolizumab);EC50=0.0153μg/mL.
Human IL31R HEK293 cells were stained with Anti-IL-31Ra Reference Antibody (nemolizumab) and negative control protein respectively; washed and then followed by PE and analyzed with FACS; EC181=0.307 μg/mL.
Anti-IL-31Ra Reference Antibody (nemolizumab) P-STAT3 Assay was evaluated using Du145. The IC50 was approximately 0.1068 ug/ml.
Anti-IL-31Ra Reference Antibody (nemolizumab) Activation inhibition was evaluated using Hacat. The max induction fold was approximately 1.86.
Quick Database Links
Gene Symbol
IL-31Ra
UniProt
UniProt Details
− No UniProt data available
Documents Download
Datasheet
Product Information
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Protocol Information
FACS
Fluorescence-Activated Cell Sorting (FC, Flow cytometry)
ELISA
Enzyme-linked Immunosorbent Assay (EIA)
IL-31Ra Antibody (orb1806167)
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