Anti-inflammatory agent 102

SKU: orb3028012

Description

Anti-inflammatory agent 102 (Compound 11a) is an orally effective anti-inflammatory compound. It exerts its effects by inhibiting the activation of the ASK1/p38 MAPKs/NF-κB signaling pathway. This agent displays significant anti-inflammatory activity by suppressing the release of NO, ROS, and inflammatory cytokines such as IL-6, TNF-α, and IL-1β. Anti-inflammatory agent 102 is applicable in research concerning inflammatory diseases, including ulcerative colitis (UC).

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	3053104-47-2
MW	333.77
Formula	C₁₆H₁₆ClN₃O₃
SMILES	O=C1N(C2=NC=CC=C2)CCN1C3=CC(Cl)=C(OC)C=C3OC
Target	NF-κB,Interleukin,NO Synthase,Reactive Oxygen Species,MAPK,MAP3K,p38 MAPK

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

NF-κB,Interleukin,NO Synthase,Reactive Oxygen Species,MAPK,MAP3K,p38 MAPK

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