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Anti-inflammatory agent 104

SKU: orb3136640

Description

Anti-inflammatory agent 104 (Compound 26) is an anti-inflammatory compound. It inhibits TNF-α synthesis and release in the U937 human macrophage cell line with an IC50 of 0.024 nM. Additionally, Anti-inflammatory agent 104 reduces eosinophil levels in rat lungs by 63%.

Images & Validation

Key Properties

CAS Number382630-23-1
MW551.07
FormulaC28H32ClFO6S
SMILESO(C(=O)C1=C(C)C=CS1)[C@@]2(C(OC)=O)[C@]3(C)[C@@](C[C@H]2C)([C@]4([C@](Cl)([C@@H](O)C3)[C@]5(C)C([C@@H](F)C4)=CC(=O)C=C5)[H])[H]
TargetTNF

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Anti-inflammatory agent 104 (orb3136640)

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