You have no items in your shopping cart.
JAK2 Rabbit Monoclonal Antibody
SKU: orb546990
Description
Research Area
Cancer Biology, Cell Biology, Epigenetics & Chromatin, Protein Biochemistry, Signal Transduction
Images & Validation
−Item 1 of 4
| Tested Applications | ICC, IF, IHC, IP, WB |
|---|---|
| Dilution Range | WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 IP 1:50-100 |
| Reactivity | Human, Mouse, Rat |
Key Properties
−| Antibody Type | Primary Antibody |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone No. | COG-10 |
| Immunogen | A synthesized peptide derived from human JAK2 Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2. |
| Target | Tyrosine-protein kinase JAK2 |
| Molecular Weight | 131 kDa |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Form/Appearance | Liquid |
| Buffer/Preservatives | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml rAlbumin. |
| Concentration | 0.5mg/ml |
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF
Similar Products
−- Item 1 of 14
Phospho-JAK2 (Tyr1007+Tyr1008) Recombinant Rabbit Monoclonal Antibody [orb559183]
ICC, IF, IHC-Fr, IHC-P
Gallus, Porcine, Rabbit
Human, Mouse, Rat
Rabbit
Recombinant
Unconjugated
25 μl, 50 μl, 100 μl - Item 1 of 3
Phospho-JAK2/JAK2 Rabbit Monoclonal Antibody [orb548526]
FC, ICC, IF, IHC, IP, WB
Human, Mouse, Rat
Rabbit
Monoclonal
Unconjugated
100 μl - Item 1 of 1
JAK2 Recombinant Rabbit Monoclonal Antibody [orb2563048]
WB
Mouse, Rat
Human
Rabbit
Recombinant
Unconjugated
25 μl, 50 μl, 100 μl 
JAK2 Rabbit monoclonal antibody [orb1677794]
WB
Human, Mouse
Rabbit
Monoclonal
Unconjugated
200 μl, 50 μl, 100 μlRecombinant JAK2 Rabbit mAb Antibody [orb2989161]
WB
Human
Rabbit
Monoclonal
Unconjugated
30 μl, 100 μl, 50 μl, 200 μl
Quality Guarantee
Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.
ICC staining JAK2 in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
WB analysis of JAK2 using anti-JAK2 antibody in Jurkat Cell.
WB analysis of JAK2 using anti-JAK2 antibody in (1) MCF-7 Cell; (2) A549 Cell; (3) rat lung Tissue.
Immunofluorescent analysis of Jurkat cells, using JAK2 Antibody.
Quick Database Links
Gene Symbol
Tyrosine-protein kinase JAK2
UniProt
UniProt Details
− No UniProt data available
Documents Download
Datasheet
Product Information
Request a Document
Protocol Information
WB
Western Blot (IB, immunoblot)
IHC
Immunohistochemistry
IF
Immunofluorescence
ICC
Immunocytochemistry
IP
Immunoprecipitation
JAK2 Rabbit Monoclonal Antibody (orb546990)
- 0.0
Based on 0 reviews
Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.
Login to Submit a ReviewAvailable Sizes
Select a size below
Usually dispatched within 2-4 weeks