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ROR1 Antibody (MMAE)
SKU: orb1805459
Description
Images & Validation
−Item 1 of 4
| Tested Applications | ELISA, FA, FACS, In vivo |
|---|---|
| Reactivity | Human |
Key Properties
−| Antibody Type | Recombinant Antibody |
|---|---|
| Clonality | Recombinant |
| Target | ROR1 |
| Source/Expression System | CHO |
| Molecular Weight | 145.12 kDa |
| Purity | >95% |
| Purification | Protein A |
| Endotoxin | <0.001 EU/ug |
| Conjugation | MMAE |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Buffer/Preservatives | 100 mM Proline/Acetic acid 20mM Arginine pH 5.0 |
| Concentration | Batch dependent |
| Disclaimer | For research use only |
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Anti-ROR1 Reference Antibody (zilovertamab vedotin) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-ROR1 Reference Antibody (zilovertamab vedotin)is more than 98.21% ;determined by SEC-HPLC.
Immobilized human ROR1 His at 2 μg/mL can bind Anti-ROR1 Reference Antibody (zilovertamab vedotin);EC50=0.002833μg/mL.
zilovertamab vedotin inhibited the tumor growth of MDA-MB-231on NSG mice. The result showed significant anti-tumor effects; with an tumor inhibition rate (TGI) of 96.6% at 10 mpk.
Quick Database Links
Gene Symbol
ROR1
UniProt
UniProt Details
− No UniProt data available
Documents Download
Datasheet
Product Information
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Protocol Information
FACS
Fluorescence-Activated Cell Sorting (FC, Flow cytometry)
ELISA
Enzyme-linked Immunosorbent Assay (EIA)
ROR1 Antibody (MMAE) (orb1805459)
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