CD8b Antibody (FITC)

SKU: orb154480

Description

Mouse monoclonal antibody conjugated to FITC which recognizes CD8B that also known as P37 and LEU2. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 binds to MHC class I and plays a role in T cell development and activation of mature T cells. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system.

Research Area

Epigenetics, Immunology

Images & Validation

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Item 1 of 2

Tested Applications	FC
Reactivity	Rat
Application Notes	Flow cytometry: Recommended dilution: 1-4 μg/ml.

Key Properties

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Antibody Type	Primary Antibody
Clonality	Monoclonal
Isotype	Mouse IgG1 kappa
Clone No.	341
Immunogen	CD8 positive Wistar rat splenic T cell hybridomas
Target	CD8b
Purification	Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Conjugation	FITC

Storage & Handling

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Storage	Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Buffer/Preservatives	Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Concentration	0.5 mg/ml
Disclaimer	For research use only

Alternative Names

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Ly-3, Ly-C, Lyt-3

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Separation of rat CD8b positive cells (red-filled) from CD8b negative cells (black-dashed) in flow cytometry analysis (surface staining) rat splenocyte suspension stained using anti-rat CD8b (341) FITC antibody (concentration in sample 1 μg/ml).

Flow cytometry surface staining pattern of rat splenocyte suspension stained using anti-rat CD8b (341) FITC antibody (concentration in sample 1 μg/ml).

Quick Database Links

Gene Symbol

CD8b

UniProt

P10966

NCBI Gene ID

926

UniProt Details

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No UniProt data available

NCBI Gene Details

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No NCBI Gene data available

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Protocol Information

Flow Cytometry

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