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TROP2 Antibody
SKU: orb1806096
Description
Images & Validation
−Item 1 of 5
| Tested Applications | ELISA, FA, FACS, In vivo |
|---|---|
| Reactivity | Human, Mouse |
Key Properties
−| Clonality | Monoclonal |
|---|---|
| Target | TROP2 |
| Source/Expression System | CHO |
| Molecular Weight | 145.52 kDa |
| Purity | >95% |
| Purification | Protein A |
| Endotoxin | <0.001 EU/ug |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Buffer/Preservatives | 100 mM Proline/Acetic acid 20mM Arginine pH 5.0 |
| Concentration | Batch dependent |
| Disclaimer | For research use only |
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Anti-TROP2 Reference Antibody (sacituzumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-TROP2 Reference Antibody (sacituzumab)is more than 96.23% ;determined by SEC-HPLC.
Immobilized human TROP2 His at 2 μg/mL can bind Anti-TROP2 Reference Antibody (sacituzumab);EC50=0.004316μg/mL.
Human TROP2 HEK293 cells were stained with Anti-TROP2 Reference Antibody (sacituzumab) and negative control protein respectively; washed and then followed by PE and analyzed with FACS; EC276=0.4071 μg/mL.
The endocytosis ratio sacituzumab by human TROP2 HEK293 increased with the increase of antibody concentration; and the Internalization Rate (%) reached 70% at antibody concentration of 0.4 nM.
Quick Database Links
Gene Symbol
TROP2
UniProt
UniProt Details
− No UniProt data available
Documents Download
Datasheet
Product Information
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Protocol Information
FACS
Fluorescence-Activated Cell Sorting (FC, Flow cytometry)
ELISA
Enzyme-linked Immunosorbent Assay (EIA)
TROP2 Antibody (orb1806096)
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