Anticancer agent 110

SKU: orb1944419

Description

Anticancer agent 110 is a cytotoxic small molecule that induces DNA damage and apoptosis. It is utilized in chronic granulocytic leukemia research, demonstrating antitumor and antileukemic activity in both in vitro cellular assays and in vivo animal models.

Research Area

Cell Biology

Images & Validation

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Key Properties

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CAS Number	887349-03-3
MW	380.399
Formula	C₁₈H₁₃FN₆OS
SMILES	FC1=CC=C(CC2=CN=C(NC(=O)C3=CC=C(C=C3)N3C=NN=N3)S2)C=C1
Target	Apoptosis

Bioactivity

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Target IC50	K562 cells:0.7 μM
In Vitro	Anticancer agent 110 exhibited an inhibitory effect on leukemic K-562 cells at concentrations ranging from 0.01 μM to 100 μM, with an IC50 value of 0.7 μM. The compound triggered higher levels of DNA damage in K-562 cells after 24 hours of treatment at concentrations of 70 nM and 700 nM, and also caused cellular morphological changes, exhibiting apoptotic features.

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Apoptosis

Quality Guarantee

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Compound Identifiers

PubChem CID

7465200 ↗

Key Properties

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No computed properties available.

Protocol Information

Find More Protocols

CAS Number:	2563879-93-4
MW:	258.26
Formula:	C₁₀H₆N₆OS

Anticancer agent 110

Description

Research Area

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

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