Apoptosis inducer 36

SKU: orb2944485

Description

Apoptosis inducer 36 (Compound 42) is a small molecule that targets leukemia stem cells (LSCs) in AML, reducing their population and promoting differentiation. It exerts anti-leukemic effects by inducing G1 phase cell cycle arrest and triggering PANoptosis, a combined form of apoptosis, pyroptosis, and necrosis, as demonstrated in cellular studies.

Research Area

Cell Biology, Immunology & Inflammation

Images & Validation

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Key Properties

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CAS Number	2831492-41-0
MW	392.647
Formula	C₂₃H₄₀O₃Si
SMILES	C[C@@]12[C@]([C@]3([C@@](CC1)(OC(=O)C(=C)C3)[H])[H])(CC[C@@H]2O[Si](C(C)C)(C(C)C)C(C)C)[H]
Target	Apoptosis,Pyroptosis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

176455407 ↗

Key Properties

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No computed properties available.

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